Federal Agencies Brace for Deep Cuts Post-'Cliff'


Dec 7, 2012 4:22pm







gty barack obama john boehner ll 121206 wblog Federal Agencies Brace for Deep Cuts Post Cliff

Toby Jorrin/AFP/Getty Images


With the “fiscal cliff” quickly approaching, federal agencies are stepping up preparations for deep automatic budget cuts that will kick in Jan. 2 unless the White House and Congress can reach a deal.


The Office of Management and Budget told ABC News that a memo went out to federal agencies earlier this week seeking “additional information and analysis” in order to finalize spending cuts required if we go off the cliff.


The agencies are considering which workers to furlough, projects to put on hold and offices that will have to close.


The request follows the administration’s release of a 400-page report in September that outlined the budget areas to be impacted by the $1.2 trillion in automatic spending cuts and what percentages they would be slashed.


READ MORE: White House Details ‘Doomsday’ Budget Cuts


Billions of dollars could be slashed from defense operations and maintenance programs. Medicare would take a two-percent hit, trimming millions in payouts to health care providers. Scientific research programs would be gutted. Aid for the poor and needy would be sharply curtailed.


The report also detailed operations that would be exempt from any cuts, including active-duty military operations, nuclear watchdogs, homeland security officials, veterans care and other critical areas.


READ: Pentagon Begins Planning for ‘Cliff’ Cuts


Asked about the agency preparations underway, White House spokesman Jay Carney said Wednesday that OMB “must take certain steps to ensure the administration is ready to issue such an order should Congress fail to act.”


“Earlier this week, OMB issued a request to federal agencies for additional information to finalize calculations on the spending reductions that would be required,” Carney said.


“This action should not be read … as a change in the administration’s commitment to reach an agreement and avoid sequestration.  OMB is simply ensuring that the administration is prepared, should it become necessary to issue such an order,” he said. “OMB will continue to consult with agencies and will provide additional guidance as needed.  This is just acting responsibly because of the potential for this happening.”


Get more pure politics at ABCNews.com/Politics and a lighter take on the news at OTUSNews.com.


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Egypt demonstrators reject Mursi call for dialogue


CAIRO (Reuters) - Demonstrators rejected a call from Egypt's Islamist President Mohamed Mursi for a national dialogue after deadly clashes around his palace, demanding the "downfall of the regime" - the chant that brought down Hosni Mubarak.


Mursi said in a televised speech late on Thursday that plans were on track for a referendum on a new constitution on December 15 despite clashes that killed seven people. He proposed a meeting on Saturday with political leaders, "revolutionary youth" and legal figures to discuss the way forward after that.


But a leading activist group rejected the offer, and fresh demonstrations were called for Friday.


The "April 6" movement, which played a prominent role in igniting the revolt against Mubarak said on its Facebook page that Friday's protests would deliver a "red card" to Mursi.


Egypt has been plunged into turmoil since Mursi issued a decree on November 22 awarding himself wide powers and shielding his decisions from judicial review.


His Islamist supporters say the decree was necessary to prevent Mubarak-era judges from interfering with reforms. A constitution drawn up by a body dominated by Islamists is due to be put to a referendum next week.


The opposition has demanded that Mursi scrap his decree, postpone the referendum and redraft the constitution.


In his address, Mursi said: "I call for a full, productive dialogue with all figures and heads of parties, revolutionary youth and senior legal figures to meet this Saturday."


Several thousand opposition protesters near the palace waved their shoes in derision after his speech and shouted "Killer, killer" and "We won't go, he will go" - another of the slogans used against Mubarak in last year's revolt.


The Cairo headquarters of the Muslim Brotherhood, the group that propelled Mursi to victory in a June election, was set ablaze. Other offices of its political party were attacked.


TENTATIVE CONCESSION


The United States, worried about the stability of an Arab partner which has a peace deal with Israel and which receives $1.3 billion a year in U.S. military aid, had urged dialogue.


Mursi said his entire decree would lapse after the constitutional referendum, regardless of its result.


He said a new constituent assembly would be formed to redraft the constitution if Egyptians rejected the one written in the past six months.


The Republican Guard, an elite unit whose duties include protecting the presidential palace, restored peace on Thursday after a night of violence outside the palace, ordering rival demonstrators to leave by mid-afternoon.


Mursi supporters withdrew, but opposition protesters remained, kept away by a barbed wire barricade guarded by tanks. By evening their numbers had swelled to several thousand.


Thousands of supporters and opponents of Mursi had fought well into Thursday's early hours, using rocks, petrol bombs and guns. Officials said 350 were wounded in the violence. Six of the dead were Mursi supporters, the Muslim Brotherhood said.


Opposition groups have called for protests after Friday prayers aimed at "the downfall of the militia regime", a dig at what they see as the Brotherhood's organized street muscle.


A communique from a leftist group urged protesters to gather at mosques and squares across Egypt, and to stage marches in Cairo and its sister city Giza, converging on the presidential palace. "Egyptian blood is a red line," the communique said.


Hardline Islamist Salafis also summoned their supporters to protest against what they consider biased coverage of the crisis by some private Egyptian satellite television channels.


Since Mursi issued his decree, six of his advisers have resigned. Essam al-Amir, the director of state television, quit on Thursday, as did a Christian official at the presidency.


The Brotherhood's supreme guide, Mohamed Badie, called for unity, saying divisions "only serve the nation's enemies".


The Islamists, who have won presidential and parliamentary elections since Mubarak was overthrown, are confident they can win the referendum and the parliamentary election to follow.


As well as relying on his Brotherhood power base, Mursi may also tap into a popular yearning for stability and economic revival after almost two years of political turmoil.


Egypt's pound hit an eight-year low on Thursday, reversing gains made on hopes that a $4.8 billion IMF loan would stabilize the economy. The stock market fell 4.6 percent.


(Additional reporting by Edmund Blair and Marwa Awad; Writing by Alistair Lyon and Peter Graff; Editing by Louise Ireland)



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Fans to get third "A Slice of Life" book






SINGAPORE: "A Slice of Life Volume 3", the third collection of scripts for the popular "A Slice of Life" self-improvement radio programme on Singapore radio station 938LIVE, will be launched on Sunday, 2pm at the &Made by Bruno Menard bistro.

Written by 938LIVE deejay Eugene Loh, "A Slice of Life Volume 3" contains the uplifting anecdotes about life, love and work, which Loh shares on his radio programme "A Slice of Life".

Loh said his book "gives certain pointers to help guide people towards understanding more about themselves, and what they can do to improve things in their life".

He added that putting his stories and observations on life into print helps people digest them more easily.

"I think people like to have something that they can carry with them," said Loh, who will be on hand to sign copies of his new book during the book launch.

"For this kind of theme as well, where it has to do with introspection, soul searching, people like to take their time, read it at their own pace, maybe digest certain phrases or lines in their own time, or maybe re-read certain chapters."

Over 1,000 copies of the book, which retails at S$16, have been pre-ordered so far.

Loh's radio programme "A Slice of Life", which currently airs every weekday between 2-5pm, has spawned a series of CDs and books, since it went on air some 14 years ago on 938LIVE.

-CNA/ha



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1993 Mumbai serial blasts result of Pak envy: Shinde

NEW DELHI: In a veiled attack on Pakistan, home minister Sushilkumar Shinde on Friday said the 1993 serial bombings in Mumbai were the result of a neighbour's envy to India's economic progress and vowed to bring back all terrorists, including Dawood Ibrahim, to face trial here.

He also said that the neighbour is still trying to weaken country's economy by pumping fake Indian currency notes.

"We launched the economic reforms in 1991 and subsequently India had achieved rapid economic progress. But a neighbour became envious of our development. Soon, there were 13 blasts in Mumbai (in 1993)," he said.

Shinde said all fugitive terrorists, including the 1993 Mumbai blasts mastermind Dawood Ibrahim, would be brought back to India and punished for their crime.

"Not only Dawood but other terrorists sitting in safe havens will be brought back to India to face trial. We are working with some international organisations," he said.

Last month, addressing the Interpol General Assembly in Rome, Shinde had said the masterminds of the heinous serial blasts are sitting in safe havens in Pakistan which has taken no action against them despite being provided with credible evidence.

Referring to circulation of fake Indian currency notes, the home minister said the nefarious design was being carried out by a neighbouring country to destroy India's economy.

"We are taking a number of steps to check the menace as economic security is paramount," he said.

The home minister said Interpol must take certain steps to apprehend those fugitives who are sitting in safe havens and getting official patronage.

Shinde said after 2008 Mumbai terror attack, the government has strengthened its intelligence gathering mechanism and was now in a better position to deal with terrorists in comparison to what it was to a few years ago.

"Due to increased vigil, we have been able to bust 19 terror module in 2012," he said, adding intensified vigilance was also helping security agencies to track down terrorists.

Shinde said so far the central government has spent Rs 12,000 crore for the modernisation of police forces and another Rs 5,000 crore will be spent for the purpose in the next five years.

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Celebrations planned as Wash. legalizes marijuana


SEATTLE (AP) — Legal marijuana possession becomes a reality under Washington state law on Thursday, and some people planned to celebrate the new law by breaking it.


Voters in Washington and Colorado last month made those the first states to decriminalize and regulate the recreational use of marijuana. Washington's law takes effect Thursday and allows adults to have up to an ounce of pot — but it bans public use of marijuana, which is punishable by a fine, just like drinking in public.


Nevertheless, some people planned to gather at 12:01 a.m. PST Thursday to smoke in public beneath Seattle's Space Needle. Others planned a midnight party outside the Seattle headquarters of Hempfest, the 21-year-old festival that attracts tens of thousands of pot fans every summer.


"This is a big day because all our lives we've been living under the iron curtain of prohibition," said Hempfest director Vivian McPeak. "The whole world sees that prohibition just took a body blow."


In another sweeping change for Washington, Gov. Chris Gregoire on Wednesday signed into law a measure that legalizes same-sex marriage. The state joins several others that allow gay and lesbian couples to wed.


That law also takes effect Thursday, when gay and lesbian couples can start picking up their wedding certificates and licenses at county auditors' offices. Those offices in King County, the state's largest and home to Seattle, and Thurston County, home to the state capital of Olympia, planned to open the earliest, at 12:01 a.m. Thursday, to start issuing marriage licenses. Because the state has a three-day waiting period, the earliest that weddings can take place is Sunday.


The Seattle Police Department provided this public marijuana use enforcement guidance to its officers via email Wednesday night: "Until further notice, officers shall not take any enforcement action — other than to issue a verbal warning — for a violation of Initiative 502."


Thanks to a 2003 law, marijuana enforcement remains the department's lowest priority. Even before I-502 passed on Nov. 6, police rarely busted people at Hempfest, despite widespread pot use, and the city attorney here doesn't prosecute people for having small amounts of marijuana.


Officers will be advising people to take their weed inside, police spokesman Jonah Spangenthal-Lee wrote on the SPD Blotter. "The police department believes that, under state law, you may responsibly get baked, order some pizzas and enjoy a 'Lord of the Rings' marathon in the privacy of your own home, if you want to."


Washington's new law decriminalizes possession of up to an ounce for those over 21, but for now selling marijuana remains illegal. I-502 gives the state a year to come up with a system of state-licensed growers, processors and retail stores, with the marijuana taxed 25 percent at each stage. Analysts have estimated that a legal pot market could bring Washington hundreds of millions of dollars a year in new tax revenue for schools, health care and basic government functions.


But marijuana remains illegal under federal law. That means federal agents can still arrest people for it, and it's banned from federal properties, including military bases and national parks.


The Justice Department has not said whether it will sue to try to block the regulatory schemes in Washington and Colorado from taking effect.


"The department's responsibility to enforce the Controlled Substances Act remains unchanged," said a statement issued Wednesday by the Seattle U.S. attorney's office. "Neither states nor the executive branch can nullify a statute passed by Congress" — a non-issue, since the measures passed in Washington and Colorado don't "nullify" federal law, which federal agents remain free to enforce.


The legal question is whether the establishment of a regulated marijuana market would "frustrate the purpose" of the federal pot prohibition, and many constitutional law scholars say it very likely would.


That leaves the political question of whether the administration wants to try to block the regulatory system, even though it would remain legal to possess up to an ounce of marijuana.


Colorado's measure, as far as decriminalizing possession goes, is set to take effect by Jan. 5. That state's regulatory scheme is due to be up and running by October 2013.


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Johnson can be reached at https://twitter.com/GeneAPseattle


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John McAfee Out of Hospital, Back in Cell













Software millionaire John McAfee has been returned to an immigration detention cell in Guatemala after being rushed to a Guatemala City hospital via ambulance.


McAfee, 67 -- who soon may be deported back to Belize, where authorities want to question him about the shooting death of his neighbor -- was reportedly found prostrate on the floor of his cell and unresponsive.


He was wheeled into the hospital on a gurney. Photographers followed in pursuit right into the emergency room, but as emergency workers eased McAfee's limp body from the gurney and onto a bed and began to remove his suit, he suddenly spoke up, saying, "Please, not in front of the press."


Earlier today, McAfee had complained of chest pains, raising concerns he might be having a heart attack.


However, that did not appear to be the case. Hours after his emergency, hospital officials sent McAfee back to the detention center, telling ABC News they found no reason to keep him overnight.


In a phone interview overnight, McAfee told ABC News, "I simply passed out, everything went black."


He said he hit his head on the floor when he collapsed. McAfee explained that for the past 48 hours he hasn't eaten and had very little to drink.


McAfee had been scheduled to be deported to Belize, ABC News has learned. But a judge could stay the ruling if it is determined that McAfee's life is threatened by being in Belizean custody, as McAfee has claimed in the past several weeks.


McAfee's attorneys hope to continue delaying the deportation by appealing to the Guatemala's high court on humanitarian grounds.


Raphael Martinez, a spokesman for the Belize government, said that if McAfee is deported to Belize, he would immediately be handed over to police and detained for up to 48 hours unless charges are brought against him.


"There is more that we know about the investigation, but that remains part of the police work," he said, hinting at possible charges.


He added that a handover by Guatemala would be "the neighborly thing to do."


A spokesman for the U.S. embassy in Guatemala said that "due to privacy considerations," the embassy would "have no comment on the specifics of this situation," but that, "U.S. citizens are subject to the laws of the countries in which they are traveling or residing, and must work within the host countries' legal framework."






Guatemala's National Police/AP Photo













Software Founder Breaks Silence: McAfee Speaks on Murder Allegations Watch Video









John McAfee Interview: Software Mogul Leaves Belize Watch Video





Just hours before McAfee's arrest, he told ABC News in an exclusive interview Wednesday he would be seeking asylum in Guatemala. McAfee was arrested by the Central American country's immigration police and not the national police, said his attorney, who was confident his client would be released within hours.


"Thank God I am in a place where there is some sanity," said McAfee before his arrest. "I chose Guatemala carefully."


McAfee said that in Guatemala, the locals aren't surprised when he says the Belizean government is out to kill him.


"Instead of going, 'You're crazy,' they go, 'Yeah, of course they are,'" he said. "It's like, finally, I understand people who understand the system here."


But McAfee added he has not ruled out moving back to the United States, where he made his fortune as the inventor of anti-virus software, and that despite losing much of his fortune he still has more money than he could ever spend.


In his interview with ABC News, a jittery, animated but candid McAfee called the media's representation of him a "nightmare that is about to explode," and said he's prepared to prove his sanity.


McAfee has been on the run from police in Belize since the Nov. 10 murder of his neighbor, fellow American expatriate Greg Faull.


During his three-week journey, said McAfee, he disguised himself as handicapped, dyed his hair seven times and hid in many different places during his three-week journey.


He dismissed accounts of erratic behavior and reports that he had been using the synthetic drug bath salts. He said he had never used the drug, and said statements that he had were part of an elaborate prank.


Investigators said that McAfee was not a suspect in the death of the former developer, who was found shot in the head in his house on the resort island of San Pedro, but that they wanted to question him.


McAfee told ABC News that the poisoning death of his dogs and the murder just hours later of Faull, who had complained about his dogs, was a coincidence.


McAfee has been hiding from police ever since Faull's death -- but Telesforo Guerra, McAfee's lawyer in Guatemala, said the tactic was born out of necessity, not guilt.


"You don't have to believe what the police say," Guerra told ABC News. "Even though they say he is not a suspect they were trying to capture him."


Guerra, who is a former attorney general of Guatemala, said it would take two to three weeks to secure asylum for his client.


According to McAfee, Guerra is also the uncle of McAfee's 20-year-old girlfriend, Samantha. McAfee said the government raided his beachfront home and threatened Samantha's family.


"Fifteen armed soldiers come in and personally kidnap my housekeeper, threaten Sam's father with torture and haul away half a million dollars of my s***," claimed McAfee. "If they're not after me, then why all these raids? There've been eight raids!"


Before his arrest, McAfee said he would hold a press conference on Thursday in Guatemala City to announce his asylum bid. He has offered to answer questions from Belizean law enforcement over the phone, and denied any involvement in Faull's death.






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Tanks outside Egypt presidential palace, streets calmer


CAIRO (Reuters) - Egyptian army tanks deployed outside the presidential palace on Thursday in streets where supporters and opponents of President Mohamed Mursi had clashed into the early hours of the morning in violence that killed five people.


Armored troop carriers also moved into the roads around the palace, in what Egypt's state news agency said was a measure to secure the palace. The area had become a chaotic battleground between Mursi's Islamist backers and their opponents.


The soldiers' badges identified them as members of the Presidential Guard and Republican Guard, whose duties include guarding the presidency. At least five tanks and nine armored personnel carriers were seen near or around the palace.


The health ministry said five people had been killed and 350 wounded in bloodshed that has exacerbated the worst crisis since Mursi took office as Egypt's first president since a popular uprising overthrew Hosni Mubarak in February, 2011.


The military played a crucial role in ending Mubarak's 30-year rule by taking over from him to manage a transitional period, but it has stayed out of the latest crisis.


Mursi's opponents accuse him of seeking to create a new autocracy by awarding himself extraordinary powers in a decree on November 22 and were further angered when an Islamist-dominated assembly pushed through a draft constitution that opponents said did not properly represent the aspirations of the whole nation.


The president has defended his decree as necessary to prevent courts still full of judges appointed by Mubarak from derailing a constitution vital for Egypt's political transition.


Around the palace, traffic was moving through streets strewn with rocks thrown during violence in which petrol bombs and guns were also used. Hundreds of Mursi supporters were still in the area, many wrapped in blankets and some reading the Koran.


"We came here to support President Mursi and his decisions. He is the elected president of Egypt," said demonstrator Emad Abou Salem, 40. "He has legitimacy and nobody else does."


MUTUAL ACCUSATIONS


An opposition group called for more protests at the palace later on Thursday, setting the stage for further confrontation.


Mursi's opponents say the Muslim Brotherhood, the group that propelled the president to power in a June election, is behind the violence. The Brotherhood says the opposition is to blame and that the five dead were all Mursi supporters. The United States, worried about the stability of an Arab state which has a peace deal with Israel and which receives $1.3 billion in U.S. military aid, urged dialogue. Britain also called for restraint and an "inclusive" political process.


A presidential source said Mursi, silent in the last few days, was expected to make a statement later on Thursday.


Vice President Mahmoud Mekky proposed "personal ideas" for a negotiated way out on Wednesday, saying amendments to disputed articles in the constitution could be agreed with the opposition. A written agreement could then go to parliament, to be elected after a referendum on the constitution on December 15.


"There must be consensus," he told a news conference in the presidential palace as fighting raged outside on Wednesday. But the opposition stuck by its demand for Mursi to cancel the November 22 decree and postpone the referendum before any dialogue.


Protests spread to other cities, and offices of the Muslim Brotherhood's political party in Ismailia and Suez were torched.


But Mursi has shown no sign of buckling under pressure from protesters, confident that the Islamists, who have dominated both elections since Mubarak was overthrown, can win the referendum and parliamentary election to follow.


As well as relying on his Brotherhood power base, Mursi may also draw on a popular yearning for stability and economic revival after almost two years of political turmoil.


Opposition coordinator Mohamed ElBaradei said on Wednesday the street action and the polarization of society were pushing Egypt into violence and "could draw us to something worse".


The Egyptian pound plunged 4 percent on Thursday to its lowest level in eight years, after previously firming on hopes that a $4.8 billion IMF loan would stabilize the economy. The Egyptian stock market fell 4.4 percent after it opened.


(Additional reporting by Reuters TV; Tamim Elyan, Yasmine Saleh and Tom Perry, Writing by Edmund Blair and Tom Perry; Editing by Alistair Lyon and Giles Elgood)



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Companies urged to tap on educated, economically inactive women






SINGAPORE: Minister in the Prime Minister's Office Grace Fu has urged companies to employ highly-educated women who are economically inactive to meet the current shortages in the labour market.

Speaking at a dialogue on developing an alternative workforce this morning, Ms Fu said this group is an important source of untapped talent.

Currently, there are about 60,000 female university graduates who are not in the workforce.

About 80 corporate leaders and HR practitioners took part in the dialogue.

Among the things discussed were measures on how to promote a family-friendly work culture.

Ms Fu said many women are often caught in a dilemma on whether to stay at home or to continue working.

Ms Fu added: "Given our demographic challenges, the employers, workplaces, should encourage more women to do both -- having a family and having a career together.

"It also benefits employers because they are able to retain their workers better, and they are also able to attract women to return to the workplace, thus, achieving both the objectives of the society and also of the employers."

- CNA/lp



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Supreme Court pulls up Centre on appointment of National Green Tribunal head

NEW DELHI: The Supreme Court on Thursday pulled up the Centre for its failure in putting on file the present Chief Justice of India's letter relating to the appointment of the chairman of National Green Tribunal (NGT), which is functioning without its head for a year.

"You have placed the record but where is the letter of the present CJI? Why you have not placed it when you knew that the matter will be taken at 10.30 am today? It's not acceptable.. the manner in which the things are going. We don't know what is happening?," a bench comprising justices G S Singhvi and S J Mukhopadhaya said.

The bench made the remark after going through the file relating to the appointment placed before it by Additional Solicitor General (ASG) A S Chandhiok.

The bench was upset that the matter was "lingering" despite the NGT being "without head" for the last one year.

"We have our own doubts about the manner in which it is being done. We are not sure when the chairman will be appointed," the bench said and reminded the ASG about its previous order of May 3 when the Centre had assured the court that things will be completed.

"It has not happened and it is very unfortunate," the court said.

On May 3, the Centre had submitted before the court that six expert and four judicial members would be appointed by October 31, however, the court had directed it to complete the process of appointments of the NGT chairman as well as its expert and judicial members by September 15.

The court on Thursday asked the Centre to give an undertaking as to by what time it would come out with the notification on appointment of the chairman and the judicial and expert members for the NGT.

The bench said it would take up the matter on Wednesday and would like the ASG to take instructions also on the issue of making available accommodation to the chairman and the judicial and expert members as per their previous status.

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Study could spur wider use of prenatal gene tests


A new study sets the stage for wider use of gene testing in early pregnancy. Scanning the genes of a fetus reveals far more about potential health risks than current prenatal testing does, say researchers who compared both methods in thousands of pregnancies nationwide.


A surprisingly high number — 6 percent — of certain fetuses declared normal by conventional testing were found to have genetic abnormalities by gene scans, the study found. The gene flaws can cause anything from minor defects such as a club foot to more serious ones such as mental retardation, heart problems and fatal diseases.


"This isn't done just so people can terminate pregnancies," because many choose to continue them even if a problem is found, said Dr. Ronald Wapner, reproductive genetics chief at Columbia University Medical Center in New York. "We're better able to give lots and lots of women more information about what's causing the problem and what the prognosis is and what special care their child might need."


He led the federally funded study, published in Thursday's New England Journal of Medicine.


A second study in the journal found that gene testing could reveal the cause of most stillbirths, many of which remain a mystery now. That gives key information to couples agonizing over whether to try again.


The prenatal study of 4,400 women has long been awaited in the field, and could make gene testing a standard of care in cases where initial screening with an ultrasound exam suggests a structural defect in how the baby is developing, said Dr. Susan Klugman, director of reproductive genetics at New York's Montefiore Medical Center, which enrolled 300 women into the study.


"We can never guarantee the perfect baby but if they want everything done, this is a test that can tell a lot more," she said.


Many pregnant women are offered screening with an ultrasound exam or a blood test that can flag some common abnormalities such as Down syndrome, but these are not conclusive.


The next step is diagnostic testing on cells from the fetus obtained through amniocentesis, which is like a needle biopsy through the belly, or chorionic villus sampling, which snips a bit of the placenta. Doctors look at the sample under a microscope for breaks or extra copies of chromosomes that cause a dozen or so abnormalities.


The new study compared this eyeball method to scanning with gene chips that can spot hundreds of abnormalities and far smaller defects than what can be seen with a microscope. This costs $1,200 to $1,800 versus $600 to $1,000 for the visual exam.


In the study, both methods were used on fetal samples from 4,400 women around the country. Half of the moms were at higher risk because they were over 35. One-fifth had screening tests suggesting Down syndrome. One-fourth had ultrasounds suggesting structural abnormalities. Others sought screening for other reasons.


"Some did it for anxiety — they just wanted more information about their child," Wapner said.


Of women whose ultrasounds showed a possible structural defect but whose fetuses were called normal by the visual chromosome exam, gene testing found problems in 6 percent — one out of 17.


"That's a lot. That's huge," Klugman said.


Gene tests also found abnormalities in nearly 2 percent of cases where the mom was older or ultrasounds suggested a problem other than a structural defect.


Dr. Lorraine Dugoff, a University of Pennsylvania high-risk pregnancy specialist, wrote in an editorial in the journal that gene testing should become the standard of care when a structural problem is suggested by ultrasound. But its value may be incremental in other cases and offset by the 1.5 percent of cases where a gene abnormality of unknown significance is found.


In those cases, "a lot of couples might not be happy that they ordered that test" because it can't give a clear answer, she said.


Ana Zeletz, a former pediatric nurse from Hoboken, N.J., had one of those results during the study. An ultrasound suggested possible Down syndrome; gene testing ruled that out but showed an abnormality that could indicate kidney problems — or nothing.


"They give you this list of all the things that could possibly be wrong," Zeletz said. Her daughter, Jillian, now 2, had some urinary and kidney abnormalities that seem to have resolved, and has low muscle tone that caused her to start walking later than usual.


"I am very glad about it," she said of the testing, because she knows to watch her daughter for possible complications like gout. Without the testing, "we wouldn't know anything, we wouldn't know to watch for things that might come up," she said.


The other study involved 532 stillbirths — deaths of a fetus in the womb before delivery. Gene testing revealed the cause in 87 percent of cases versus 70 percent of cases analyzed by the visual chromosome inspection method. It also gave more information on specific genetic abnormalities that couples could use to estimate the odds that future pregnancies would bring those risks.


The study was led by Dr. Uma Reddy of the National Institute of Child Health and Human Development.


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Online:


Medical journal: http://www.nejm.org


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Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP


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